Product Name

Application

Region

ME001-Tumour suppressor mix 1

(basic research)

Tumour suppressor genes

Various

ME002-Tumour suppressor mix 2

(basic research)

Tumour suppressor genes

Various

ME011-MMR

Mismatch repair genes (MMR)

MLH1, MSH2, MSH6, MLH3, MSH3, PMS2, MGMT

ME012-MGMT-IDH1-IDH2

Gliomas

MGMT, IDH1, IDH2

ME024-9p21

Tumours, Cutaneous melanoma

9p21, CDKN2A, CDKNA2B

ME042-CIMP

(basic research)

CpG Island Methylator Phenotype

Various

P004-ERBB2

Cancer

ERBB2 (HER2-NEU) 17q21.1

P014-Chromosome 8

Tumour research

Chromosome 8

P027-Uveal melanoma

Uveal melanoma

1p, chr.3, 6p, 8q

P047-RB1

Retinoblastoma (RB)

RB1 13q14

P056-TP53

Li-Fraumeni syndrome (LFS) and tumour analysis

TP53 17p13.1

P063-FHIT-WWOX

Diverse tumour types, epileptic encephalopathy

FHIT (3p14.2) and WWOX (16q23.1)

P078-Breast tumour

Breast tumour

various

P083-CDH1

Hereditary diffuse gastric cancer

CDH1 at 16q22.1

P088-Oligodendroglioma 1p-19q

Oligodendroglioma

1p, 19q, IDH1/2, CDKN2A/2B

P105-Glioma-2

Glioma, malignant

EGFR, TP53, PTEN + various other

P146-CRC GAIN

(basic research)

Colon cancer

Various

P157-20q region

Colon cancer, breast cancer and various others

20q (BCL2L1, MYBL2, ZNF217, DNMT3B, AURKA, GNAS)

P175-Tumour Gain

(basic research)

Tumour Gain

various

P181-Centromere mix 1

Centromeric screening

Centromeres

P182-Centromere mix 2

Centromeric testing

Centromeres

P215-EXT

Multiple Osteochondromas

EXT1 8q24, EXT2 11p11

P225-PTEN

Cowden syndrome and tumour analysis

PTEN 10q23

P251-NB mix 1

Neuroblastoma

1p36, 3p22/3p21.3 and 11q23

P252-NB mix 2

Neuroblastoma

2p24.1/MYCN, 2q33, 17p13/TP53, 17q

P253-NB mix 3

Neuroblastoma

Chromosomes 4, 7, 9, 12, 14

P258-SMARCB1

Rhabdoid tumors

SMARCB1 22q11.2

P294-Tumour Loss

(basic research)

Tumour Loss

various

P298-BRAF-HRAS-KRAS-NRAS

(basic research)

Various tumour types

BRAF, HRAS, KRAS, NRAS

P301-Medulloblastoma mix 1

Medulloblastoma

Chr. 6, Chr. 14, Chr. 16, Chr. 17.

P302-Medulloblastoma mix 2

Medulloblastoma

Chr. 2, Chr. 3, Chr. 7, Chr. 9

P303-Medulloblastoma mix 3

Medulloblastoma

Chr. 1, Chr. 4, Chr. 5, Chr. 8, Chr. 10, Chr. 20

P308-MET

Papillary renal carcinoma, various cancers

MET 7q31, PTEN 10q23.31, LRRK2 12q12

P315-EGFR

Tumours, solid

EGFR 7p11

P323-CDK4-HMGA2-MDM2

Sarcoma and other tumour types

chromosome 12, MDM2, CDK4 and HMGA2 genes

P370-BRAF-IDH1-IDH2

(basic research)

Gliomas

BRAF, IDH1, IDH2, FGFR1, MYB, MYBL1, CDKN2A

P376-BRCA1ness

BRCA1-like breast cancer profile

various

P378-MUTYH

Colon cancer, stomach cancer (hereditary)

1p34 and 15q13

P380-Wilms' tumour

Wilms' tumour

various

P413-CRC LOSS

(basic research)

Colorectal adenoma/carcinoma

8p, 15q, 17p, 18q

P417-BAP1

Melanocytic tumours, mesothelioma

BAP1, 3p21.1

P419-CDKN2A/2B-CDK4

Familial melanoma

CDKN2A, CDKN2B, CDK4, MITF E318K

P429-SDHA-MAX

Paraganglioma and pheochromocytoma

5p15.3 and 14q23.3

P433-ARID1A-ARID1B

Neuroblastoma, ovarian cancer + various other tumour types + mental retardation

ARID1A, ARID1B

P448-PARD3

PARD3

10p11.21-p11.22

P455-LZTR1

Schwannomatosis

22q11.21

P458-Gastric cancer

Gastric cancer

various

P466-CDC73

HPT jaw tumour syndrome, famial hyperparathyroidism, parathyroid carcinoma

CDC73

P472-SUFU

Familial Medulloblastoma and Meningioma

10q24.32